he classical 147Sm−143Nd radiogenic isotopic system has been extensively used in geochemistry and cosmochem- istry as a powerful geochemical tracer or chronometer since the 1970s.1,2 High precision ratios of 143Nd/144Nd and 147Sm/144Nd are prerequisites for dating and tracing purposes.

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Usually, reproducibility of ≤0.003% for 143Nd/144Nd ratio and ≤1% for 147Sm/144Nd ratio is required in geochronological and geochemical studies. Isotope dilution mass spectrometry (IDMS) technique is considered to be a primary method that can produce excellent accuracy and precision.3,4 Isotope dilution thermal ionization mass spectrometry (ID-TIMS) technique5−11 and isotope dilution multiple-collector induc- tively coupled plasma mass spectrometry (ID-MC-ICP-MS) technique12−15 have been used for achieving accurate and precise results for Sm−Nd. MC-ICP-MS offers high efficiency for precise isotopic ratio measurements with high sample throughputs.12−16 When a laser ablation is coupled with MC-ICP-MS, in situ analysis of tiny mineral grains with high concentrations of Sm−Nd (>200 ppm at least), such as apatite, monazite, and perovskite can be done.17−20 However, compared to TIMS, the cost of the MC- ICP-MS instrument and operation is higher. In addition, MC- ICP-MS suffers much larger mass bias and more complicated isobaric interferences of oxides and/or argides.21 On the other hand, TIMS generally offers better sensitivity and precision for Sm−Nd measurements. For example, the external precision of 143Nd/144Nd in a Nd standard (Ames) reached the level of ±2 ppm using TIMS.22 The excellent precision in Sm−Nd data was obtained using TIMS even at very small sample size down to 1 ng.10,11,23 Hence, both Sm−Nd isotopic compositions and elemental contents are traditionally performed by TIMS, considered as the benchmark technique.10,22,24 To achieve accurate Sm and Nd isotopic data in geological samples, all isobaric interferences (144Sm on 144Nd, 148Sm on 148Nd, and 150Sm on 150Nd) need to be eliminated. Tradition- ally, after sample digestion and sample-spike (149Sm−150Nd) equilibration, Sm and Nd fractions are completely separated from the matrix solutions using the classical two-step cation exchange chromatography technique before TIMS measure- ments.5−10,14,15,22−29 After the solution dried, the purified Sm and Nd fractions from spiked samp

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